Simultaneous Determination of Cocaine, Cocaethylene, and Their Possible Pentafluoropropylated Metabolites and Pyrolysis Products by Gas Chromatography/Mass Spectrometry
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منابع مشابه
The ability of bacterial cocaine esterase to hydrolyze cocaine metabolites and their simultaneous quantification using high-performance liquid chromatography-tandem mass spectrometry.
Cocaine toxicity is a widespread problem in the United States, responsible for more than 500,000 emergency department visits a year. There is currently no U.S. Food and Drug Administration-approved pharmacotherapy to directly treat cocaine toxicity. To this end, we have developed a mutant bacterial cocaine esterase (DM-CocE), which has been previously shown to rapidly hydrolyze cocaine into ine...
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تاریخ انتشار 2003